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Early history [ edit ] The site of what later became the city of Saginaw was originally inhabited by the Anishnabeg. French missionaries and traders first appeared in the area during the late 17th century and encountered the Ojibwe (Chippewa) living in the area. The first permanent settlement by those other than Native Americans was in 1816 when Louis Campau established a trading post on the west bank of the Saginaw River. Shortly thereafter the United States established Fort Saginaw. Campau's trading post was also inhabited by Metis.